Estudo de Carga Global de Doença (Global Burden of Disease) – GBD Brasil

Apresentação

O Estudo GBD emprega várias ferramentas analíticas e diversas fontes de dados para gerar estimativas comparáveis de número de óbitos, taxas de mortalidade, incidência e prevalência de doenças e anos vividos com incapacidade, segundo idade, sexo, causa, ano e localização geográfica. A abordagem analítica do GBD para estimação é guiada por soluções padronizadas para problemas analíticos gerais: inconsistência em definições ou códigos para diferentes épocas ou áreas geográficas; dados faltantes; dados contraditórios para um mesmo ano e localização; e grupos populacionais (por exemplo: população de baixa renda, minorias e grupos vulneráveis) que são frequentemente omitidos em fontes de dados administrativos. Trata-se de descrição epidemiológica das causas de mortalidade, sofrimento e riscos à saúde. O GBD mostra, de forma padronizada e com livre acesso, as doenças e suas causas, indicadores de mortalidade relacionados a fatores de risco, informações por países e regiões do mundo, por sexo e idade, em um período de duas décadas e meia, além de outras variedades de dados possíveis.

Publicações relacionadas:

Wulf Hanson S, Abbafati C, Aerts JG, Al-Aly Z, Ashbaugh C, Ballouz T, Blyuss
O, Bobkova P, Bonsel G, Borzakova S, Buonsenso D, Butnaru D, Carter A, Chu H, De Rose C, Diab MM, Ekbom E, El Tantawi M, Fomin V, Frithiof R, Gamirova A, Glybochko PV, Haagsma JA, Javanmard SH, Hamilton EB, Harris G, Heijenbrok-Kal MH, Helbok R, Hellemons ME, Hillus D, Huijts SM, Hultström M, Jassat W, Kurth F, Larsson IM, Lipcsey M, Liu C, Loflin CD, Malinovschi A, Mao W, Mazankova L, McCulloch D, Menges D, Mohammadifard N, Munblit D, Nekliudov NA, Ogbuoji O, Osmanov IM, Peñalvo JL, Petersen MS, Puhan MA, Rahman M, Rass V, Reinig N, Ribbers GM, Ricchiuto A, Rubertsson S, Samitova E, Sarrafzadegan N, Shikhaleva A, Simpson KE, Sinatti D, Soriano JB, Spiridonova E, Steinbeis F, Svistunov AA, Valentini P, van de Water BJ, van den Berg-Emons R, Wallin E, Witzenrath M, Wu Y, Xu H, Zoller T, Adolph C, Albright J, Amlag JO, Aravkin AY, Bang-Jensen BL, Bisignano C, Castellano R, Castro E, Chakrabarti S, Collins JK, Dai X, Daoud F, Dapper C, Deen A, Duncan BB, Erickson M, Ewald SB, Ferrari AJ, Flaxman AD, Fullman N, Gamkrelidze A, Giles JR, Guo G, Hay SI, He J, Helak M, Hulland EN, Kereselidze M, Krohn KJ, Lazzar-Atwood A, Lindstrom A, Lozano R, Magistro B, Malta DC, Månsson J, Mantilla Herrera AM, Mokdad AH, Monasta L, Nomura S, Pasovic M, Pigott DM, Reiner RC, Reinke G, Ribeiro ALP, Santomauro DF, Sholokhov A, Spurlock EE, Walcott R, Walker A, Wiysonge CS, Zheng P, Bettger JP, Murray CJ, Vos T. A global systematic analysis of the occurrence, severity, and recovery pattern of long COVID in 2020 and 2021. medRxiv [Preprint]. 2022 May 27:2022.05.26.22275532. doi: 10.1101/2022.05.26.22275532. PMID: 35664995; PMCID: PMC9164454. Link.

COVID-19 Excess Mortality Collaborators. Estimating excess mortality due to the COVID-19 pandemic: a systematic analysis of COVID-19-related mortality, 2020-21. Lancet. 2022 Apr 16;399(10334):1513-1536. doi: 10.1016/S0140-6736(21)02796-3. Epub 2022 Mar 10. Erratum in: Lancet. 2022 Apr 16;399(10334):1468. PMID: 35279232; PMCID: PMC8912932. Link.

GBD 2019 Ageing Collaborators. Global, regional, and national burden of diseases and injuries for adults 70 years and older: systematic analysis for the Global Burden of Disease 2019 Study. BMJ. 2022 Mar 10;376:e068208. doi: 10.1136/bmj-2021-068208. PMID: 35273014. Link.

GBD 2019 Diabetes Mortality Collaborators. Diabetes mortality and trends before 25 years of age: an analysis of the Global Burden of Disease Study 2019. Lancet Diabetes Endocrinol. 2022 Mar;10(3):177-192. doi: 10.1016/S2213-8587(21)00349-1. Epub 2022 Feb 7. PMID: 35143780; PMCID: PMC8860753. Link.

COVID-19 National Preparedness Collaborators. Pandemic preparedness and COVID-19: an exploratory analysis of infection and fatality rates, and contextual factors associated with preparedness in 177 countries, from Jan 1, 2020, to Sept 30, 2021. Lancet. 2022 Apr 16;399(10334):1489-1512. doi: 10.1016/S0140-6736(22)00172-6. Epub 2022 Feb 1. PMID: 35120592; PMCID: PMC8806194. Link.

Cousin E, Schmidt MI, Stein C, Aquino ÉC, Gouvea ECDP, Malta DC, Naghavi M, Duncan BB. Premature mortality due to four main non-communicable diseases and suicide in Brazil and its states from 1990 to 2019: A Global Burden of Disease Study. Rev Soc Bras Med Trop. 2022 Jan 28;55(suppl 1):e0328. doi: 10.1590/0037-8682-0328-2021. PMID: 35107541; PMCID: PMC9009436. Link.

Stein C, Schmidt MI, Cousin E, Malta DC, Naghavi M, Oliveira PPV, Ribeiro ALP, Duncan BB. Exposure to and Burden of Major Non-Communicable Disease Risk Factors in Brazil and its States, 1990-2019: The Global Burden of Disease Study. Rev Soc Bras Med Trop. 2022 Feb 7;55(suppl 1):e0275. doi: 10.1590/0037-8682-0275-2021. PMID: 35107511; PMCID: PMC9022946. Link.

GBD 2019 Stroke Collaborators. Global, regional, and national burden of stroke and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Neurol. 2021 Oct;20(10):795-820. doi: 10.1016/S1474-4422(21)00252-0. Epub 2021 Sep 3. PMID: 34487721; PMCID: PMC8443449. Link.

GBD 2019 Collaborators. Global mortality from dementia: Application of a new method and results from the Global Burden of Disease Study 2019. Alzheimers Dement (N Y). 2021 Jul 27;7(1):e12200. doi: 10.1002/trc2.12200. PMID: 34337138; PMCID: PMC8315276. Link.

GBD 2019 Tobacco Collaborators. Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019. Lancet. 2021 Jun 19;397(10292):2337-2360. doi: 10.1016/S0140-6736(21)01169-7. Epub 2021 May 27. Erratum in: Lancet. 2021 Jun 19;397(10292):2336. PMID: 34051883; PMCID: PMC8223261. Link.

GBD 2019 Hearing Loss Collaborators. Hearing loss prevalence and years lived with disability, 1990-2019: findings from the Global Burden of Disease Study 2019. Lancet. 2021 Mar 13;397(10278):996-1009. doi: 10.1016/S0140-6736(21)00516-X. PMID: 33714390; PMCID: PMC7960691. Link.

Stein C, Cousin E, Machado ÍE, Felisbino-Mendes MS, Passos VMA, Sousa TM, Schmidt MI, Gallagher J, Naghavi M, Duncan BB. The COVID-19 Pandemic in Brazil: Institute for Health Metrics and Evaluation projections and observed evolution, May-August, 2020. Epidemiol Serv Saude. 2021 Feb 5;30(1):e2020680. English, Portuguese. doi: 10.1590/S1679-49742021000100017. PMID: 33566896. Link.

Roth GA, Mensah GA, Johnson CO, Addolorato G, Ammirati E, Baddour LM, Barengo NC, Beaton AZ, Benjamin EJ, Benziger CP, Bonny A, Brauer M, Brodmann M, Cahill TJ, Carapetis J, Catapano AL, Chugh SS, Cooper LT, Coresh J, Criqui M, DeCleene N, Eagle KA, Emmons-Bell S, Feigin VL, Fernández-Solà J, Fowkes G, Gakidou E, Grundy SM, He FJ, Howard G, Hu F, Inker L, Karthikeyan G, Kassebaum N, Koroshetz W, Lavie C, Lloyd-Jones D, Lu HS, Mirijello A, Temesgen AM, Mokdad A, Moran AE, Muntner P, Narula J, Neal B, Ntsekhe M, Moraes de Oliveira G, Otto C, Owolabi M, Pratt M, Rajagopalan S, Reitsma M, Ribeiro ALP, Rigotti N, Rodgers A, Sable C, Shakil S, Sliwa-Hahnle K, Stark B, Sundström J, Timpel P, Tleyjeh IM, Valgimigli M, Vos T, Whelton PK, Yacoub M, Zuhlke L, Murray C, Fuster V; GBD-NHLBI-JACC Global Burden of Cardiovascular Diseases Writing Group. Global Burden of Cardiovascular Diseases and Risk Factors, 1990-2019: Update From the GBD 2019 Study. J Am Coll Cardiol. 2020 Dec 22;76(25):2982-3021. doi: 10.1016/j.jacc.2020.11.010. Erratum in: J Am Coll Cardiol. 2021 Apr 20;77(15):1958-1959. PMID: 33309175; PMCID: PMC7755038. Link.

GBD 2019 Risk Factors Collaborators. Global burden of 87 risk factors in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020 Oct 17;396(10258):1223-1249. doi: 10.1016/S0140-6736(20)30752-2. PMID: 33069327; PMCID: PMC7566194. Link.

GBD 2019 Diseases and Injuries Collaborators. Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020 Oct 17;396(10258):1204-1222. doi: 10.1016/S0140-6736(20)30925-9. Erratum in: Lancet. 2020 Nov 14;396(10262):1562. PMID: 33069326; PMCID: PMC7567026. Link.

GBD 2019 Viewpoint Collaborators. Five insights from the Global Burden of Disease Study 2019. Lancet. 2020 Oct 17;396(10258):1135-1159. doi: 10.1016/S0140-6736(20)31404-5. PMID: 33069324; PMCID: PMC7116361. Link.

Felisbino-Mendes MS, Cousin E, Malta DC, Machado ÍE, Ribeiro ALP, Duncan BB, Schmidt MI, Silva DAS, Glenn S, Afshin A, Velasquez-Melendez G. The burden of non-communicable diseases attributable to high BMI in Brazil, 1990-2017: findings from the Global Burden of Disease Study. Popul Health Metr. 2020 Sep 30;18(Suppl 1):18. doi: 10.1186/s12963-020-00219-y. PMID: 32993699; PMCID: PMC7525961. Link.

França E, Ishitani LH, Teixeira R, Duncan BB, Marinho F, Naghavi M. Changes in the quality of cause-of-death statistics in Brazil: garbage codes among registered deaths in 1996-2016. Popul Health Metr. 2020 Sep 30;18 (Suppl 1):20. doi: 10.1186/s12963-020-00221-4. PMID: 32993689; PMCID: PMC7526091. Link.

Malta DC, Duncan BB, Schmidt MI, Teixeira R, Ribeiro ALP, Felisbino-Mendes MS, Machado ÍE, Velasquez-Melendez G, Brant LCC, Silva DAS, Passos VMA, Nascimento BR, Cousin E, Glenn S, Naghavi M. Trends in mortality due to non-communicable diseases in the Brazilian adult population: national and subnational estimates and projections for 2030. Popul Health Metr. 2020 Sep 30;18(Suppl 1):16. doi: 10.1186/s12963-020-00216-1. PMID: 32993685; PMCID: PMC7525955. Link.

Duncan BB, Cousin E, Naghavi M, Afshin A, França EB, Passos VMA, Malta D, Nascimento BR, Schmidt MI. The burden of diabetes and hyperglycemia in Brazil: a global burden of disease study 2017. Popul Health Metr. 2020 Sep 30;18(Suppl 1):9. doi: 10.1186/s12963-020-00209-0. PMID: 32993680; PMCID: PMC7526086. Link.

Nascimento BR, Brant LCC, Yadgir S, Oliveira GMM, Roth G, Glenn SD, Mooney M, Naghavi M, Passos VMA, Duncan BB, Silva DAS, Malta DC, Ribeiro ALP. Trends in prevalence, mortality, and morbidity associated with high systolic blood pressure in Brazil from 1990 to 2017: estimates from the “Global Burden of Disease 2017” (GBD 2017) study. Popul Health Metr. 2020 Sep 30;18(Suppl 1):17. doi: 10.1186/s12963-020-00218-z. PMID: 32993676; PMCID: PMC7526365. Link.

de David CN, Deligne LMC, da Silva RS, Malta DC, Duncan BB, Passos VMA, Cousin E. The burden of low back pain in Brazil: estimates from the Global Burden of Disease 2017 Study. Popul Health Metr. 2020 Sep 30;18(Suppl 1):12. doi: 10.1186/s12963-020-00205-4. PMID: 32993673; PMCID: PMC7526352. Link.

de Azeredo Passos VM, Champs APS, Teixeira R, Lima-Costa MFF, Kirkwood R, Veras R, Nascimento BR, Nogales AM, Schmidt MI, Duncan BB, Cousin E, Naghavi M, Souza FM. The burden of disease among Brazilian older adults and the challenge for health policies: results of the Global Burden of Disease Study 2017. Popul Health Metr. 2020 Sep 30;18(Suppl 1):14. doi: 10.1186/s12963-020-00206-3. PMID: 32993668; PMCID: PMC7524597. Link.

GBD 2019 Universal Health Coverage Collaborators. Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020 Oct 17;396(10258):1250-1284. doi: 10.1016/S0140-6736(20)30750-9. Epub 2020 Aug 27. PMID: 32861314; PMCID: PMC7562819. Link.

LBD Double Burden of Malnutrition Collaborators. Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017. Nat Med. 2020 May;26(5):750-759. doi: 10.1038/s41591-020-0807-6. Epub 2020 Apr 20. Erratum in: Nat Med. 2020 Jul 2;: PMID: 32313249; PMCID: PMC7220891. Link.

GBD Chronic Kidney Disease Collaboration. Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2020 Feb 29;395(10225):709-733. doi: 10.1016/S0140-6736(20)30045-3. Epub 2020 Feb 13. PMID: 32061315; PMCID: PMC7049905. Link.

GBD 2017 Cirrhosis Collaborators. The global, regional, and national burden of cirrhosis by cause in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet Gastroenterol Hepatol. 2020 Mar;5(3):245-266. doi: 10.1016/S2468-1253(19)30349-8. Epub 2020 Jan 22. PMID: 31981519; PMCID: PMC7026710. Link.

Status: Em andamento
Início: Maio/2019

Conclusão prevista: Janeiro/2024
Eixo temático:
Hipertensão Arterial, Diabetes Mellitus, Obesidade e Terapias

Eixo metodológico:
Pesquisas Epidemiológicas
Instituição coordenadora:
UFRGS

Instituição participante:
Institute of Health Metrics and Evaluation
Fonte de fomento:
FAPERGS
Coordenação: 
Bruce Duncan (UFRGS)

Integrantes:
Maria Inês Schmidt (UFRGS)
Ricardo de Souza Kuchenbecker (UFRGS)
Bárbara Niegia Garcia de Goulart (UFRGS)

Links relacionados:

CORREIO DO POVO. Pesquisa aponta que nenhuma dose de álcool é recomendável: https://www.correiodopovo.com.br/vivabem/saude/pesquisa-aponta-que-nenhuma-dose-de-%C3%A1lcool-%C3%A9-recomend%C3%A1vel-1.322183

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